Molecular machines that maintain chromosome structure organise DNA by pulling it into loops, but they do it one-sided and can even switch directions.
New paper with contributions from our Peters lab!
New paper with contributions from our Peters lab!
Reposted from
Cees Dekker
New discovery from our #CDlab reported in Cell @cp-cell.bsky.social today:
SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion!
www.sciencedirect.com/science/arti...
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SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion!
www.sciencedirect.com/science/arti...
1/
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