What‘s the pathophysiology behind aortic aneurysm in bicuspid aortic valve?
Is it
A) genetic-based aortic tissue properties or
B) hemodynamic shear stress?
1/2
Is it
A) genetic-based aortic tissue properties or
B) hemodynamic shear stress?
1/2
Comments
BAV with fused cusps and raphe with ascending aneurysm probably has more shear-stress etiology and the true bicuspid with root dilatation more likely a genetic background (some have Loeys-Dietz without other features).
https://www.nejm.org/doi/full/10.1056/NEJMra1207059?logout=true