Yes, still waiting for that subcellular-scale imaging of membrane voltage (with kilohertz sampling) across hundreds or thousands of neurons in an awake-behaving animal. Oh, and up to 1 mm deep, too, please. Then comes all the analysis...
In this nice and straightforward formulation you dont consider we know already something about those beta. External (e.g. theoretical) constraints can reduce the overall variance. How do you think we could factor in theory?
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