A few more letters... and we can finally write amino acid sequence with protein structure encoded by amino acid sequence? 🧬🤔😀 @chrisfrank662.bsky.social , Dominik Schiwietz, Lara Fuss, Hendrik Dietz www.biorxiv.org/content/10.1... - ThreadSky

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sokrypton.org • 96 days ago

A few more letters... and we can finally write amino acid sequence with protein structure encoded by amino acid sequence? 🧬🤔😀

@chrisfrank662.bsky.social , Dominik Schiwietz, Lara Fuss, Hendrik Dietz
https://www.biorxiv.org/content/10.1101/2024.11.21.624687v1

Comments

phantomas1234.bsky.social•96 days ago

Nice, protein rich alphabet soup!

megthescientist.bsky.social•91 days ago

One day I can 3-d print my name from proteins :)

lindorfflarsen.bsky.social•91 days ago

Try pdbwords https://github.com/KULL-Centre/pdbwords

megthescientist.bsky.social•91 days ago

😱 okay, will report back maybe with some prints soon!!

proteinmagnus.bsky.social•96 days ago

This should be a key goal for de novo design efforts 😀

az-mtl.bsky.social•96 days ago

This will likely happen before we get an emoji for proteins and stop relying on the alpha helix one 🥲.

marleyhalston.bsky.social•95 days ago

paulmoodyoxford.bsky.social•96 days ago

How about the letters here?
https://www.nature.com/articles/nsmb.3011

sokrypton.org•96 days ago

But could they be read easily via nsTEM? 🙃

krapnik.bsky.social•96 days ago

Yes! have you deposited them to PDB?

especially letter K is enigma among protein structures there…

sokrypton.org•96 days ago

Don't think PDB allows deposit of structures only confirmed via nsTEM...

krapnik.bsky.social•96 days ago

then my #3dprint-able protein alphabet will be still noncomplete - so far, I have approx. 2/3 of alphabet…

yalim.bsky.social•95 days ago

Sharing to science feed
🧪

andrewfeig.bsky.social•96 days ago

Reminds me of an old paper from the Journal of Irreproducible Results on how to tell T-cells from B-cells based on micrographs that had T-shaped and B-shaped internal structures respectively. Now out of print and offline unfortunately - would have liked to post the figure for reference.

arneelof.bsky.social•96 days ago

Cool.

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