New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction.
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
https://www.biorxiv.org/content/10.1101/2025.04.29.651207v1
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
https://www.biorxiv.org/content/10.1101/2025.04.29.651207v1
Comments
Applying it to the actin fusion focus, an #actin aster that underlies yeast #cell_fusion, we show stereotypical order and compaction of the structure.
The movie shows coincident formin Fus1 (green) and myosin V Myo52 (magenta) signals converging together.
It is conceptually remarkably similar to how spindle poles form. It seems like the same principles apply to form cytoskeletal asters, whether based on actin or microtubules.
#actin #microtubules #cytoskeleton