Excited to share our latest findings, now published @NatureNeuro https://www.nature.com/articles/s41593-024-01813-1
We found unmyelinated axons exhibit pearls-on-a-string morphology's due to their membrane mechanical properties.
Threads will follow!
We found unmyelinated axons exhibit pearls-on-a-string morphology's due to their membrane mechanical properties.
Threads will follow!
Comments
https://neuroglancer-demo.appspot.com/#!%7B%22dimensions%22:%7B%22x%22:%5B1e-9%2C%22m%22%5D%2C%22y%22:%5B1e-9%2C%22m%22%5D%2C%22z%22:%5B1e-9%2C%22m%22%5D%7D%2C%22position%22:%5B187429.375%2C21900.8984375%2C18960.5%5D%2C%22crossSectionOrientation%22:%5B0%2C1%2C0%2C0%5D%2C%22crossSectionScale%22:3.040503131260883%2C%22projectionOrientation%22:%5B0%2C1%2C0%2C0%5D%2C%22projectionScale%22:65536%2C%22layers%22:%5B%7B%22type%22:%22image%22%2C%22source%22:%22n5://s3://janelia-cosem-datasets/jrc_dauer-larva/jrc_dauer-larva.n5/em/tem-uint8%22%2C%22tab%22:%22rendering%22%2C%22opacity%22:1%2C%22blend%22:%22additive%22%2C%22shader%22:%22#uicontrol%20invlerp%20normalized%28range=%5B0%2C%20255%5D%2C%20window=%5B0%2C%20255%5D%29%5Cn#uicontrol%20vec3%20color%20color%28default=%5C%22white%5C%22%29%5Cnvoid%20main%28%29%7BemitRGB%28color%20%2A%20normalized%28%29%29%3B%7D%22%2C%22name%22:%22tem-uint8%22%7D%5D%2C%22selectedLayer%22:%7B%22visible%22:true%2C%22layer%22:%22tem-uint8%22%7D%2C%22crossSectionBackgroundColor%22:%22#000000%22%2C%22layout%22:%22xy%22%7D
The full dataset is linked here: https://openorganelle.janelia.org/datasets/jrc_dauer-larva
If interested in the course (June 8 – July 21, 2025), please let us know! The application is due January 27, 2025.
http://go.mbl.edu/neuroNeurobiology:
https://www.science.org/content/article/controversial-study-redraws-classical-picture-neuron
(arrows = non-synaptic varicosities, arrowheads = synaptic varicosities)
this looks like it's right up your alley!