The integrated single-cell RNA-seq object included 90,716 CNS myeloid cells, mostly microglia, 241 individual samples & 19 input datasets. We describe nine transcriptionally distinct subpopulations, one of which “Lipo.DAM” is expanded in #Alzheimer’s disease and #MultipleSclerosis
Huge thanks to all who contributed: @elimereu.bsky.social at @CarrerasIJC.bsky.social, Paulo Pinho e Costa and Bárbara Leal at @ICBAS_UPorto, and @LagunaAriadna at @VHIR_! & more!
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