Also sorry for your loss. Anesthesiologist here, but iruntbamimma is correct. Although it has potent analgesic properties, Ketamine acts primarily on NMDA receptors, not opiate receptors. It is hallucinogenic, differing in chemical structure from LSD by a single methyl group. - ThreadSky

jaybeeess.bsky.social • 63 days ago

Also sorry for your loss. Anesthesiologist here, but iruntbamimma is correct. Although it has potent analgesic properties, Ketamine acts primarily on NMDA receptors, not opiate receptors. It is hallucinogenic, differing in chemical structure from LSD by a single methyl group.

Comments

jbraund13.bsky.social•63 days ago

LSD & Ketamine don’t have similar structures at all

serafina2112.bsky.social•63 days ago

I’d just like to say that I love all of the educated people here. In the last years of Twitter, I longed to see this kind of intelligent banter.

reneehere.bsky.social•63 days ago

Yesss, nice...

maacha1.bsky.social•63 days ago

It's not just banter but intelligent and thoughtful conversation that some of us definitely appreciate very much. So thank you all.

reneehere.bsky.social•63 days ago

Agree... Think we try.. Add a little humorous relief every now and then
Here to share, support, learn... Etc

karenlartin.bsky.social•63 days ago

Appreciate your post

sbelcaptan.bsky.social•63 days ago

Isn’t ketamine used in pediatric surgery as ‘light’ anesthesia?

genderqueeries.bsky.social•63 days ago

Not just pediatric. Ketamine and propofol are used commonly for procedural sedation.

sbelcaptan.bsky.social•63 days ago

👍

genderqueeries.bsky.social•62 days ago

Indeed, a wonderful ride (that killed Micheal Jackson?) ;)

jaybeeess.bsky.social•63 days ago

I wouldn’t say it’s for “light” anesthesia, but there are reasons to use it. Someone may have told you that because you can administer ketamine and patients will tolerate noxious stimuli but continue to breathe, thus appearing to be “lightly” anesthetized.

jaybeeess.bsky.social•63 days ago

With that said, it still requires careful monitoring by qualified people. As Matthew Perry recently demonstrated.

sbelcaptan.bsky.social•63 days ago

And I guess I should have added that I’m pretty sure that in ‘normal’ times anyone being treated with ketamine would face significant scrutiny during a federal security clearance audit. Anyone exhibiting signs of dependency would have to fail said audit. Not sure that these are normal times.

sbelcaptan.bsky.social•63 days ago

Used on my toddler son to help place a PICC. I was in the room. He was o u t 😂 He’s doing great in grad school now.

maryma364.bsky.social•63 days ago

Thank you. Why is it used for end stage cancer? I sat with her that last day, and she did not seem to be in pain; my assumption was that it was the ketamine IV drip.

jaybeeess.bsky.social•63 days ago

As I said, it is a potent analgesic and is sometimes clinically useful, especially for people who have been in chronic pain, who may have become habituated to opiates, such that opiates no longer provide adequate pain relief.

maryma364.bsky.social•63 days ago

Again, that makes sense. Who knows what i heard or believed i heard. As you can imagine, it was a brutal battle and we just wanted her comfortable. Thank you for clarification.

macklesmn.bsky.social•63 days ago

This is the kind of interaction I’m here for. Thank you for continuing to ask and not shutting things down.
And very sorry for your loss. A parent shouldn’t outlive their children. Love and hugs.

iruntbamimma.bsky.social•63 days ago

My heart goes out to you ❤️We are working on better treatments. big picture her docs were right that ketamine is brought out when usual opioid regimens aren’t cutting it anymore. It’s probably “safer” drug in that it’s harder to OD, but oft requires IV and more expertise. So, it’s “beyond” opioids

jaybeeess.bsky.social•63 days ago

I cannot even imagine what it is to sit by the bedside of your child and see them suffer. It would be near-impossible to absorb everything you were told under those circumstances.

paulwinn.bsky.social•63 days ago

❤️‍🩹

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