Happy to present the peer-reviewed version of our Hydractinia Cell Atlas paper out today in Nature Communications! As I presented this back when we were in “that other” social network, let me recap the basic findings and revision items in this thread: www.nature.com/articles/s41... - ThreadSky

jordisolana.bsky.social • 48 days ago

Happy to present the peer-reviewed version of our Hydractinia Cell Atlas paper out today in Nature Communications! As I presented this back when we were in “that other” social network, let me recap the basic findings and revision items in this thread:

https://www.nature.com/articles/s41467-025-57168-z

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allancarbal.bsky.social•48 days ago

Felicidades @drsalamander.bsky.social , #PoderLatino💪🏽

mads100tist.bsky.social•48 days ago

Ole ahi!

jordisolana.bsky.social•48 days ago

So, Hydractinia: Not the hermit crab, nor the dead mollusc that once occupied the shell, but the colonial cnidarian growing on top of it. Can we learn more about how this association evolved using single-cell analysis?

jordisolana.bsky.social•48 days ago

Hydractinia symbiolongicarpus is a colonial cnidarian. The whole mat with hundreds of polyps is only one organism. Only one larva settles in the shell, and then it grows a structure made of stolons and polyps, that is intercommunicated and shares food, cells, etc.

jordisolana.bsky.social•48 days ago

Coloniality is a very interesting and enigmatic process. It challenges our views of individuality. You could think of the individual polyps as clones, but they are not: they are the same organism indeed.

jordisolana.bsky.social•48 days ago

Coloniality is also seen in other critters such as ascidians and bryozoans, for instance. The colony is just one organism, interconnected, but it has individualized and distinct parts (called zooids) that are connected by stolons

jordisolana.bsky.social•48 days ago

But: what are the cellular bases of coloniality? In other words: are the different colony parts (polyps, stolons) made of the same cell types, different cell types, or a mixture? And how did Hydractinia evolve to adapt to this niche of cohabiting mollusc shells?

jordisolana.bsky.social•48 days ago

We decided to explore this using single cell analysis (ACME and SPLiT-seq). Enter the Hydractinia Cell Atlas: 200K cells uncovering ~38 cell types of isolated Hydractinia body parts, including feeding polyps, sexual polyps and stolons.

eveseuntjens.bsky.social•48 days ago

Cool new findings in there! Congrats!

lsiexeter.bsky.social•47 days ago

Congratulations! Great to hear the good news.

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