🔬Genetic mutations in gliomas (IDH1R132H/TP53R248Q) increase chromosomal instability; cells with these are more sensitive to paclitaxel and temozolomide, suggesting new targeted therapies. Read more in NAR Cancer: https://doi.org/10.1093/narcan/zcaf003
#CancerResearch #Glioma #IDH1 #TP53 #Paclitaxel #Temozolomide