I think the consensus is that TMEM192 is a better/more stable lysosomal marker than LAMP1. I haven’t validated an antibody for endogenous 192 yet. LysoTrackers work well and can give you an indirect measurement of pH. I like LysoTracker Red DND-99.
Besides imaging with Lysotracker, you might want to evaluate their function using DQ-BSA (degradation in lysosomes results in the release of fluorescent fragments) in the presence or not of Baf A1. TFEB and related target genes are use to follow lysosome biogenesis
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https://www.pnas.org/doi/10.1073/pnas.2419079121