📚🧪 A recent human #omics + in vitro study revealed important findings in Metabolic-Associated Steatotic Liver Disease (MASLD) research. By Andrew S. Perry, Niran Hadad, Emeli Chatterjee, et al. In @cellpress.bsky.social: www.cell.com/cell-reports... - ThreadSky

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ertrunnell.bsky.social • 45 days ago

📚🧪 A recent human #omics + in vitro study revealed important findings in Metabolic-Associated Steatotic Liver Disease (MASLD) research.
By Andrew S. Perry, Niran Hadad, Emeli Chatterjee, et al.
In @cellpress.bsky.social: https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00642-6

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ertrunnell.bsky.social•45 days ago

🏥 #MASLD affects over 30% of individuals globally, contributing to liver disease and increasing the risk of cancer, heart disease, & kidney dysfunction. However, diagnosing & tracking its progression remains a challenge.

ertrunnell.bsky.social•45 days ago

🔍 The study combined large population data, #transcriptomics, & #proteomics of the human liver to uncover biomarkers for MASLD. Researchers analyzed data from 5,000 individuals & validated findings using the UK Biobank (26,000+ individuals).

ertrunnell.bsky.social•45 days ago

📊 They also used a human liver-on-a-chip to confirm these findings & understand the disease’s dynamic progression. This translational approach identified potential targets for #MASLD diagnosis and prognosis.
#onachip #MPS #NAMs

ertrunnell.bsky.social•45 days ago

Congratulations to the authors, including
@nebanovich.bsky.social
@mjbetti.bsky.social
@timkendall.bsky.social
@janefreedmanmd.bsky.social
@intmedabel.bsky.social
@charlottelscott.bsky.social
of
@vanderbilt.edu
@tgenresearch.bsky.social
@edinburgh-uni.bsky.social
& more

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