Have you been thinking hard about statistical modelling of scATAC-seq data? (No.)
Luckily for you, @aaronkwc.bsky.social has!
Aaron will help you grok:
What's going on?
What is TF-IDF?
Is there really single-cell level chromatin information?
Check it out ๐
https://www.biorxiv.org/content/10.1101/2024.12.04.626927v1
๐งช๐งฌ๐ป
Luckily for you, @aaronkwc.bsky.social has!
Aaron will help you grok:
What's going on?
What is TF-IDF?
Is there really single-cell level chromatin information?
Check it out ๐
https://www.biorxiv.org/content/10.1101/2024.12.04.626927v1
๐งช๐งฌ๐ป
Comments
Aaron presents a simple generative model for scATAC-seq data that gives insights into what is (and isn't) possible with inference from scATAC-seq data.
Scrutinisation, insights, provocative thoughts...
Read it, ponder it, continue discussions - let us know what you think!