1) Here it is, our overview of the most interesting ME/CFS studies of 2024. If you think we’re missing an important one, feel free to post it as a comment below 👇 mecfsskeptic.com/202... - ThreadSky

mecfsskeptic.bsky.social • 64 days ago

1) Here it is, our overview of the most interesting ME/CFS studies of 2024.

If you think we’re missing an important one, feel free to post it as a comment below 👇
https://mecfsskeptic.com/2024-looking-back-on-a-year-of-me-cfs-research/

Comments

phillyhart4.bsky.social•57 days ago

📌

drgeraldcoakley.bsky.social•64 days ago

Incredibly helpful review of the last year’s published research in ME/CFS. Thanks for taking the time to compile this summary and including the links

kikicurious.bsky.social•64 days ago

Bergquist did some really interesting digging into metabolic alterations with respect to ME/CFS pathogenesis: https://pubs.acs.org/doi/10.1021/acschemneuro.4c00444

kikicurious.bsky.social•64 days ago

Also I haven't read this yet but it's a review article that tries to make the case for neuroglial failure being at the root of alll

https://www.frontiersin.org/articles/10.3389/fncel.2022.888232/full

mecfsskeptic.bsky.social•64 days ago

Thanks for sharing!

drglammie.bsky.social•61 days ago

📌

mecfsskeptic.bsky.social•64 days ago

2) A recent preprint used data from the UK Biobank and showed that there are many differences in the blood between ME/CFS patients and controls.

Their analysis suggests that these differences are not due to inactivity or deconditioning.

mecfsskeptic.bsky.social•64 days ago

3) The Intramural NIH study did the most extensive set of biological measurements ever conducted in ME/CFS patients but because of the low sample size (n = 17) and focus on ‘effort preference’ it has mostly led to disappointment.

mecfsskeptic.bsky.social•64 days ago

4) The MCAM study recruited patients from 7 ME/CFS specialty clinics and assessed cognitive functioning in more than 200 patients.

Accuracy was relatively normal but information processing speed was significantly lower in patients versus controls.

mecfsskeptic.bsky.social•64 days ago

5) This year, the largest study on repeated cardiopulmonary exercise testing in ME/CFS was published. Although there were small to moderate effects, there was a large overlap between patients and controls. It is unclear if this procedure can be used as a diagnostic test.

mecfsskeptic.bsky.social•64 days ago

6) 2024 also saw two big rehabilitation trials for children with ME/CFS: MAGENTA and FITNET-NHS. Both had null results suggesting that GET and online CBT (FITNET) are unlikely to be cost-effective.

mecfsskeptic.bsky.social•64 days ago

7) We also had a new prevalence estimate using statistics data for NHS Hospitals in England. Extrapolating the highest rates to the entire UK would mean that 390.000 people (0.585%) get ME/CFS in their lifetime.

annekevliegen.bsky.social•64 days ago

How can this still be going on?!

jesshoneybadger.bsky.social•61 days ago

📌

jesshoneybadger.bsky.social•63 days ago

📌

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