Ahh it's out!!🤩 Deniz finds new functions for MLL3/4 (KMT2C/D) and H3K4me1 in regulating DNA replication timing and origin activity in ESCs.
My unused CUT&Tag data from my PhD found its forever home-- and it was recycled by Deniz in such a brilliant fashion to make these discoveries!! 🥹
My unused CUT&Tag data from my PhD found its forever home-- and it was recycled by Deniz in such a brilliant fashion to make these discoveries!! 🥹
Reposted from
Deniz Gökbuget
🚨 New Paper Alert! 🚨
Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: www.cell.com/cell-reports.... More info ⬇️
Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: www.cell.com/cell-reports.... More info ⬇️
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