Checkout the latest work by our #MSKPostdoc @sukritsingh92.bsky.social
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Sukrit Singh
New preprint! We prospectively evaluate structure-based methods and measure how well they classify clinical kinase mutations as inhibitor–resistant or –sensitizing when compared against our NanoBRET assay. Alchemical methods are well-suited to modeling distal mutants! Link: doi.org/10.1101/2024...
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