Speaking of things you don't usually see on a cartridge (but also in the game itself): the Japanese version of Lester the Unlikely (1994) features an emoticon in its title: (^^;
https://gamemanual.midnightmeattrain.com/entry/%E3%81%8A%E3%81%A7%E3%81%8B%E3%81%91%E3%83%AC%E3%82%B9%E3%82%BF%EF%BD%9E_%E3%82%8C%E3%82%8C%E3%82%8C%E3%81%AE%E3%82%8C%28%5E%5E%3B
https://gamemanual.midnightmeattrain.com/entry/%E3%81%8A%E3%81%A7%E3%81%8B%E3%81%91%E3%83%AC%E3%82%B9%E3%82%BF%EF%BD%9E_%E3%82%8C%E3%82%8C%E3%82%8C%E3%81%AE%E3%82%8C%28%5E%5E%3B
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https://youtu.be/3S-QSjNDU9Q?t=436