Our story in PNAS today!
(1) anti-AR molecules with new mechanism: induction of chromatin binding YET a disruption of transcription
(2) why only ~150 genes respond to AR ligands, despite the 6,000+ AR binding sites: they need 3D clustering to matter!
https://www.pnas.org/doi/10.1073/pnas.2406239121
(1) anti-AR molecules with new mechanism: induction of chromatin binding YET a disruption of transcription
(2) why only ~150 genes respond to AR ligands, despite the 6,000+ AR binding sites: they need 3D clustering to matter!
https://www.pnas.org/doi/10.1073/pnas.2406239121
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