IHC showed it to co-express keratins, S100 protein, SOX10 and SMA (not shown). NGS found a FUS::KLF17 fusion, one of the more common pediatric myoepithelioma fusions. This one was clinically benign, but most pediatric myoepitheliomas are malignant.
In the bowel you mean? No. There aren’t in many places where we get “myoepitheliomas” in soft tissue and bone. Most rhabdos don’t occur where there is skeletal muscle, either. We’ve kind of ceased worrying about “cell of origin”.
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https://pubmed.ncbi.nlm.nih.gov/38782103/