Mitochondria sense bacterial lactate & drive release of neutrophil extracellular traps.

Neutrophil #mitochondria sense metabolic perturbations in the phagosome.
Accumulation of bacterial #lactate is a metabolic danger signal triggering #NETosis.

https://www.cell.com/cell-host-microbe/abstract/S1931-3128(25)00051-4?dgcid=raven_jbs_aip_email #ImmunoSky #MicroSky