I am so excited to share our new study published in @jama.com Psychiatry! Including >240,000 women (>8,000 patients with endometriosis), we found that patients reported more childhood and adulthood traumatic experiences. @renatopolimanti.bsky.social @lokhammer.bsky.social - ThreadSky

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dorakoller.bsky.social • 28 days ago

I am so excited to share our new study published in @jama.com Psychiatry!

Including >240,000 women (>8,000 patients with endometriosis), we found that patients reported more childhood and adulthood traumatic experiences.
@renatopolimanti.bsky.social @lokhammer.bsky.social

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dorakoller.bsky.social•28 days ago

These experiences included sexual, physical, and emotional traumas (see the results of our LCA below). We also observed that contact traumas (traumatic events involving physical contact with the abuser) also occured more frequently in patients.

dorakoller.bsky.social•28 days ago

We also conducted genetic correlation analyses between endometriosis and 23 trauma-related phenotypes, with the strongest associations observed for PTSD and childhood maltreatment.

dorakoller.bsky.social•28 days ago

Endometriosis PRS was associated with the disease itself, but we found no interaction with traumatic events, suggesting that trauma assessment could help identify individuals at higher risk.

dorakoller.bsky.social•28 days ago

Our findings support the necessity of trauma-informed care in endometriosis. This could even help avoiding further delays on the top of the average 7-10 years in the diagnosis of the disease.

dorakoller.bsky.social•28 days ago

Thank you so much everyone who contributed to the study!

We used publicly available data from the UKB, FinnGen, IEGC, PGC, and other smaller cohorts. We are so grateful to the researchers who shared these data!

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