The world is full of crazy and sad news, but here is a protein that localizes to only one of the two flagella - ThreadSky

bungoakiyoshi.bsky.social • 26 days ago

The world is full of crazy and sad news, but here is a protein that localizes to only one of the two flagella

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mcbleicester.bsky.social•26 days ago

😀

howarthsci.bsky.social•20 days ago

I love it- that's wild.

robinsall.bsky.social•26 days ago

🎼🎼🎼 you put your left leg in, you take your left leg out
in, out, in, out, wave it all about
you do the Chlamy cokey and you spin around 🎵🎵🎵🎵

bungoakiyoshi.bsky.social•26 days ago

♩♩♩I forgot to say this is not Chlamy but a long-neglected marine plankton called Diplonema papillatum♩♩♩

jmorri2.bsky.social•26 days ago

Lovely!

luskinglab.bsky.social•25 days ago

Cool! Reminds me of asymmetric localization of spindle pole body proteins in yeast (old, mother versus new, daughter).

stearnslab.bsky.social•23 days ago

Lots of things with two flagella have one “tinsel” flagellum and one “whiplash” flagellum. Possible?

bungoakiyoshi.bsky.social•23 days ago

That would be interesting but unlikely. Such difference has not been observed by EM. Also these flagella should have similar age

bungoakiyoshi.bsky.social•23 days ago

Actually I cannot say about the age of these two flagella. I don't know how basal bodies/flagella get duplicated and segregated in this organism

vartak.bioimaging.tech•25 days ago

Counld it be that these are unconventionally placed anterior and posterior flagella? https://en.wikipedia.org/wiki/Stramenopile

bungoakiyoshi.bsky.social•25 days ago

I am not an expert of flagella biology but the two flagella in this organism are reported to be identical by EM observation so it was surprising to see this localization pattern.

micromotility.bsky.social•26 days ago

amazing! what does this protein actually do... any ideas??

bungoakiyoshi.bsky.social•26 days ago

No idea but I will first need to spend some time looking at the sequence properly. Looks like conserved in Bodo and Naegleria (two flagella), not in tryps (one flagellum)

barrygoldman1.bsky.social•25 days ago

wait... this critter is related to euglena? but Naegleria is not? please explain, and what is tryps abbrevation for?

bungoakiyoshi.bsky.social•25 days ago

Yes. Diplonemids belong to Euglenozoa that also includes euglenids and kinetoplastids (including Bodo and tryps: trypanosomes). Naegleria is not part of Euglenozoa, but has this protein.

burnsajohn.bsky.social•26 days ago

I don't feel great right now, but this made me feel a little better. Thanks for sharing. And the #protistsonsky feed might like it too.

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