In the truest sense and if we were to take a page from peripheral inflammation, Neuro inflammation needs to have multiple immune cell types participate. T/B/NK/PMNs/macrophages. Because microglia have an important role in CNS homeostasis activation could just be a response to dyshomeostasis
Reposted from
Dr Ramesh Raghupathi
What isn’t neuroinflammation - a single parameter of change (morphology or molecular). The bigger question for me is whether astrocyte changes without microglia changes qualify as inflammation. To me microglia are better indicators of inflammation
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