After pinging w/ my fam, probably options D and C b/c my mom has had both and her sister has one (or both, not sure) trapezium bone removed due to arthritis.
Genetics for the win again.
Genetics for the win again.
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However compensating for one with the other is exhausting overall - even when it's not my originally dominant hand that's having the issue.
That is flared up for unknown reasons.
And I'm being recommended hand/thumb specific PT and have my ring splints checked over for proper fit (that thumb one is old to be fair)