So excited about this new work on Bayesian optimization for antibody design! It works by teaching a generative model how the human immune system evolves antibodies for strong and stable binders. Satisfying mix of ML+Bio. Check out the great thread from @alannawzadamin.bsky.social and the paper!
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Alan Amin
How do you go from a hit in your antibody screen to a suitable drug? Now introducing CloneBO: we optimize antibodies in the lab by teaching a generative model how we optimize them in our bodies!
w/ Nat Gruver, Yilun Kuang, Lily Li, @andrewgwils.bsky.social and the team at Big Hat! 1/7
w/ Nat Gruver, Yilun Kuang, Lily Li, @andrewgwils.bsky.social and the team at Big Hat! 1/7
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