In our study, now available on #bioRxiv, Cristian—along with June (see previous post on Bluesky), Juan Montenegro, and others—applied single-nuclei sequencing, using a newly sequenced and assembled Spadella genome as a reference.
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This allowed us to identify the transcriptomic profiles of the cells involved in attachment, neuronal populations, and key cell types in chaetognath hatchlings.
Additionally, we identified diverse cell types in the ventral nerve center and validated multiple ciliated cell types previously described through anatomical observations.
Ongoing investigations, integrating data from other developmental stages in our lab, will provide deeper insights into the evolutionary origins of the unique chaetognath body plan.
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