Yeast #proteotoxic stress response: Intrinsically disordered protein Roq1 reprograms specificity of #ubiquitin ligase Ubr1 towards four distinct classes of substrates using its N-terminal arginine linked to a short hydrophobic motif
Sebastian Schuck and colleagues
https://www.embopress.org/doi/full/10.1038/s44318-025-00375-7