New Study just out in The Lancet Global Health! #LucasDaRos, @vbwyll.bsky.social, #CristianoAguzzoli & colleagues used a machine learning model to determine the most important risk factors for cognitive and functional decline in Brazil and other LATAM Countries 🧵 www.thelancet.com/journals/lan... - ThreadSky

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zimmerneurolab.bsky.social • 27 days ago

New Study just out in The Lancet Global Health! #LucasDaRos, @vbwyll.bsky.social, #CristianoAguzzoli & colleagues used a machine learning model to determine the most important risk factors for cognitive and functional decline in Brazil and other LATAM Countries 🧵 https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(24)00451-0/fulltext

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zimmerneurolab.bsky.social•27 days ago

🧩 Social and health determinants were more significant than classical demographics risk factors in all Latin American Countries, with important differences among them. 🧵2

zimmerneurolab.bsky.social•27 days ago

📊 Education emerged as the most impactful risk factor for cognitive decline in Brazil, while Mental Health was the most impactful for functional deterioration. 🧵3

zimmerneurolab.bsky.social•27 days ago

We could also see an impact of Brazilian geographical regions in the model for predicting risk factors for cognitive and functional decline. We evidenced worst cognitive scores in North and Northeast, while only Northeast presented worst functional scores. 🧵4

zimmerneurolab.bsky.social•27 days ago

📣 Our findings point out the significance of individually understanding the risk factors for cognitive impairment and dementia in each specific region, rather than adopting a generalist, broad, one-size-fits-all approach. 🧵5

zimmerneurolab.bsky.social•27 days ago

💪 This work was a team effort from Brazil: @ufrgs.br, #PPGBioq, #PPGFarmaco, and #InsCer. 🧵6

zimmerneurolab.bsky.social•27 days ago

We thank the co-authors: #MarcoDeBastiani, #JadersonCostaDaCosta, #TharickAPascoal, #PedroRosaNeto, #LucasPSchilling, @santamaria-garcia.bsky.social, #AgustinMIbanez, @claudiasuemoto.bsky.social,
and @erzimmer.bsky.social. 🧵7

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