Super cool paper shared to me by @handleyg.bsky.social on the use of dur/sul addition to either imipenem or cefoxitin in the treatment of M abscessus Group. #IDSky #PharmSky #MycoSky https://journals.asm.org/doi/10.1128/aac.01046-24
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It is kinda trivial anyway to revolutionize antibiotics potency, safety and reverse resistance, e.g. by actually making a gram negative permeating variant (e.g. liposomal) of fusific acid. The fact is isn't being marketed is peak worlwide mediocrity. https://pmc.ncbi.nlm.nih.gov/articles/PMC10885999/
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https://pmc.ncbi.nlm.nih.gov/articles/PMC10885999/