Have you ever thought of using a fluorescent probe to specifically enrich and profile proteins with disordered regions?

Read below about RUBICON (reactive unfolded protein-based identification of cysteine on enrichment), a new workflow which enables the identification of the disordered proteome!
🎆 New #ToolsOfTheTrade 🎆

@shouxiang-zhang.bsky.social & owyongtc.bsky.social ( @yuninghong.bsky.social lab @latrobeuni.bsky.social )
profile disordered proteins using a chemical tag. Check out the workflow and potential applications below!

🔗 go.nature.com/414Qtfv

OG paper: go.nature.com/4i3AGok

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