Less is sometimes more! 💪🏻🔥
NSAIDs have a ceiling dose. Ketorolac 10 mg may be just as effective as 30 mg but side effects like bleeding are dose-related. #medsky #pharmsky #EMSky #SkyRx
https://pubmed.ncbi.nlm.nih.gov/27993418/
NSAIDs have a ceiling dose. Ketorolac 10 mg may be just as effective as 30 mg but side effects like bleeding are dose-related. #medsky #pharmsky #EMSky #SkyRx
https://pubmed.ncbi.nlm.nih.gov/27993418/
Comments
But still - why give > 10mg if there is no benefit
That’s correct, this particular paper didn’t show ↑ SEs but other papers generally have shown ↑ bleeds w/ ↑ doses (>10mg) and duration (>5d).
https://pubmed.ncbi.nlm.nih.gov/8569017/
Absolutely, if no additional benefit & other data showing risk, why give more? :)