Beautiful video of inter-cellular signaling in a swarming response that I pulled from the other place, produced by @strickland-evelyn.bsky.social in collaboration with D. Irimia lab.
The dye detects calcium flux that indicates a signal being received by each cell: you're seeing the 'alarm' go out.
The dye detects calcium flux that indicates a signal being received by each cell: you're seeing the 'alarm' go out.
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Inflammatory cascades can amplify & cause tissue damage if not constrained, so the pulse has to be damped, 'self-terminating'.
More of Dr. Strickland's excellent work is here via pre-print BioRxiv:
"Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming" Dev Cell. 2024 Oct 7;59(19):2659-2671.e4.
Sometimes the system appears more than the sum of its parts.
Science is a collective, public, international effort that benefits all of humanity & dimming its light anywhere dims it everywhere.
🧪