Pretty cool! Ability to do long-read metagenomes is often limited by DNA input. PacBio's new SPRQ chemistry increases data output, reduces input req to 500ng. More importantly, the more you multiplex the less input you need. Multiplex 2 samples, req is 250ng and so on.

https://www.pacb.com/blog/lighting-a-sprq-how-new-revio-chemistry-fuels-innovative-research/