Yes, the pessimist in me thinks that one protracted infection may be enough for this to happen. Or there is something we are missing that makes H5N1 just really bad at getting to h2h transmission.
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But I keep thinking that there may be something to the "human club"-hypothesis after all.
https://bsky.app/profile/erictopol.bsky.social/post/3lcle7gul4k2k