A good thread by @angierasmussen.bsky.social on the recent #h5n1 cases and the question of why some people
might be getting much sicker than others. It’s a good hypothesis and I wish there was more data to try and figure out if it’s right (and to answer a range of other questions).
Reposted from Angie Rasmussen
For months now, the CDC has described H5N1 as “mild” compared to prior H5N1 viruses. I disagree—the virus alone doesn’t determine pathogenicity.

I hypothesize that the 2 most critical determinants of H5N1 severity are the host (it’s always the host 🥰) & the route of infection.

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