On March 5, 2025, from 19:30 (March 4), russia launched 3 Iskander-M/KN-23 missiles, 1 S-300 missile, and 181 Shahed UAVs/simulators from multiple directions.

Ukraine's defenses shot down 115 UAVs and 55 drone simulators. Kyiv,

Odesa, Dnipropetrovsk, and Kharkiv suffered damage.