With a Markov model, we deconvolved when, in frame t-1, there is one cancer cell and one T cell in a window, and in frame t there is one cancer cell and two T cells. We were able to quantify how often this doubling of T cells attacking a cancer cell was due to proliferation or due to recruitment.
Comments
https://www.biorxiv.org/content/10.1101/2024.10.01.616134v1
https://github.com/vanvalenlab/Caliban-2024_Schwartz_et_al
https://github.com/bee-hive/occident
Thank you to @bioimagearchive.bsky.social for hosting these Incucyte image data -- this is a new thing for them, and they have been so kind in working through the details of submission (link coming soon!)! 🎉