Crystalis was so goooood. I'm still angry to this day that they butchered the GBC port, and then decided that it not selling meant no one wanted more. It should be a franchise like Legend of Zelda now! Just thinking about it has half the music stuck in my head.
The GBC one made some significant changes to the storyline that weren't well liked, shortened the final dungeon, removed some plot points, and replaced the entire amazing soundtrack of the original NES one with a much weaker one. You're much better playing the NES original.
They also didn't change the enemy attack routines to account for the smaller GBC screen so you can get attacked by enemies you can't even see with no idea what's happening.
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Difficulty was dumbed down heavily, and they cut the whole final boss part too.* :)
Yes, she was being facetious.