Wonderful discussion.

On one end we have the 1989 PettyBone RCT and on the other the 1948 Bradford Hill RCT.

Then the spectrum between them.

While we disagree on the history and past mandates of of the PettyBone lumping Paradigm, Ed has hit it out of the park with his thoughtful response.
Reposted from Ed Palmer
This has been quite a lively debate on trials in intensive care. I don't think the "pathological science" chat is productive, but I'm always up for a healthy scientific debate. Thoughts on datamethods: discourse.datamethods.org/t/the-petty-... @statsepi.bsky.social @load-dependent.bsky.social

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