Our work on K63-polyubiquitin in membrane trafficking is out! Check out how we use a high affinity and specific sensor for K63-polyUb to identify K63-polyubiquitylated plasma membrane proteins in clusters of vesicles containing ATG9A.
Link: https://www.molbiolcell.org/doi/10.1091/mbc.E24-12-0535
Link: https://www.molbiolcell.org/doi/10.1091/mbc.E24-12-0535
Comments
Many thanks to Sharon Lian for all the help with experiments and Tingting Yao and Bob Cohen for their mentoring and funding. The beautiful CLEM images were obtained by Evaa-Liisa Eskelinen.