It’s been my pleasure to illustrate science for @dikiclab.bsky.social @idikic.bsky.social @uxiagestal.bsky.social and Dr. Lina Heraus on their publication titled “IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion” published in Cell this month!
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highlights the role of IRGQ in MHC-I quality control. Here, a hepatocellular carcinoma cell is shown as a busy factory producing garden scissors, that symbolize MHC-I molecules with light and heavy chains.
up unassembled or discarded, resulting in unproductive chain production and signaling in cells.
(text adapted from Heraus et al. cover submission)