CDC has never had authority to give or enforce mandates. CDC is essentially an advisor. States implement that advice to varying degrees. When republicans say they want to reform CDC's authority they mean remove the ability to make recommendations. This is exactly what Project 2025 calls for.
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You can't fool mother nature. The diseases will still be there. The pandemic will still kill you whether you acknowledge it or not.
Cuts US off from the knowledge base from around the world.
Not knowing will mean you won't be prepared nor know how to prepare.