Is anyone making causal claims? I was intrigued about “functional connectivity”due to its name in grad school, but when I learned what it really was, I wasn’t particularly confused about it.
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Almost all functional connectivity articles I see seem to use functional connectivity / correlation in methods section and causal language in discussion.
Still not making "causal claims"... But opto-genetics stimulation is changing the picture significantly though.
In math, the do-operator is used to model causality and set some variables to a value. Opto-genetics inactivation sets the activity to 0 in the middle of a network trajectory.
So I fully agree with the blog of @kordinglab.bsky.social , and it's just a matter of time before important papers analyze fruitfully opto-genetics data with causality theories. We tried to contribute a bit: https://www.biorxiv.org/content/10.1101/2024.09.27.615361v3
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In math, the do-operator is used to model causality and set some variables to a value. Opto-genetics inactivation sets the activity to 0 in the middle of a network trajectory.