I learned about this meropenem/VPA drug interaction the hard way as a new practitioner after unsuccessfully dose titrating VPA for days (and wasting 💰). Fortunately VPA indication was for alcohol withdrawal (non benzo ICU protocol at Stanford), not seizures!
See useful tidbits on this interaction👇
See useful tidbits on this interaction👇
Reposted from
Stanford Antimicrobial Safety & Sustainability Program
🌟 ABX Pearl of the Day: drug interaction carbapenems + valproic acid
💡 Q: I’d like to start meropenem for an ESBL E. coli infection in my patient who is also on valproic acid (VPA). What should I be aware of?
#IDsky #Medsky #MedEd #PharmSky #SkyRX
💡 Q: I’d like to start meropenem for an ESBL E. coli infection in my patient who is also on valproic acid (VPA). What should I be aware of?
#IDsky #Medsky #MedEd #PharmSky #SkyRX
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