I’m super happy to have a great part of my PhD work (under the wonderful supervision of C. Libourel @pierremarcdelaux.bsky.social & @maximebonhomme.bsky.social) now out in @naturegenet.bsky.social ! Here’s a little thread (1/18) www.nature.com/articles/s41... - ThreadSky

chloe-beaulieu.bsky.social • 8 days ago

I’m super happy to have a great part of my PhD work (under the wonderful supervision of C. Libourel @pierremarcdelaux.bsky.social & @maximebonhomme.bsky.social) now out in @naturegenet.bsky.social !
Here’s a little thread (1/18)
https://www.nature.com/articles/s41588-024-02071-4

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chloe-beaulieu.bsky.social•8 days ago

After years of collaborative sampling, we brought together a collection of 133 accessions from
Europe (@pierremarcdelaux.bsky.social, P. Szovenyi, F. Roux & the Great British Liverwort Hunt (led by @davidjhoey.bsky.social , @ilichenmoss2.bsky.social , E. Moyroud and @dromius.bsky.social) (2/18)

chloe-beaulieu.bsky.social•8 days ago

But also from Northern America (J. Nelson) and from Japan, distributed between the three subspecies of Marchantia polymorpha (16 from ssp. montivagans, 14 from ssp. polymorpha and 103 from ssp. ruderalis) (3/18)

chloe-beaulieu.bsky.social•8 days ago

All accessions were sequenced in short reads (D. Mbadinga, @karimaelm.bsky.social, C. Girou, I. Diop) + 2 sequenced in long reads (@inrae-cnrgv.bsky.social & and A. Braeutigam H. Wiebke, S. Zachgo, A. Meierhenrich, B. Laker), producing new assembled genomes for Marchantia polymorpha (4/18)

chloe-beaulieu.bsky.social•8 days ago

Short read mapping on the reference genome allowed to uncover 12 million SNPs in the 3 ssp (5.3 millions in ssp. ruderalis alone)
We now had a great resource to study the genetic diversity in this bryophyte! (available on Marpolbase https://marchantia.info/pangenome/, thanks to Y. Tanizawa) (5/18)

chloe-beaulieu.bsky.social•8 days ago

First, we took a look at the population structure of M. polymorpha. There is no genetic x geographic correlation, suggesting gene flow and recombination across the large geographical range of M. polymorpha ssp. ruderalis (6/18)

chloe-beaulieu.bsky.social•8 days ago

Then we identified genes under selective pressure in M. polymorpha, and noticed that Marchantia’s polymorphic genes are likely to mediate the interactions between the plant and its environment (e.g. pathogenesis related proteins, lectins or peroxidases) (7/18)

michel-oxyberg.bsky.social•5 days ago

Félicitations! Tu es superbe 😊

eveteyssier.bsky.social•8 days ago

Congrats ✨

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