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50shadesofgreg.bsky.social
Dad, Medical Science Liaison, former bio prof, monkey brain aficionado, lover of Monorails, PeopleMovers, and large cantilevered concrete terraces with janky water features. Opinions are my own and not my employer's. He/they.
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Time to get to know how we know about sodium channels, a very helpful tool to control pain. Hint: It was a massive, diverse, collective endeavor supported by federal investment in research institutions. And scorpions and spiders whose venoms do all sorts of weird shit to those channels. 🧪

YES Another example from a librarian I heard this morning: the patron who came in with a list of ILL requests, half of which were unfulfillable because the LLM they queried MADE THE BOOKS UP 📚

A few years ago, my friend, outspoken climate scientist Peter Kalmus @climatehuman.bsky.social, moved his family out of LA because he could extrapolate from the data. This week the house where he raised his kids burned down. His words for us all (gift link): 🧪 www.nytimes.com/2025/01/10/o...

NYE in the ER always hurts my heart because we run traumas on people in the nicest clothes, whose evenings started with such excitement and promise. No one plans to be with us, but you can plan to avoid us: *public transit *ride share *designated sober driver *talk to your teens about their plans

Influenza vaccines for this year are about 50% effective against all severity of influenza in adults and slightly more effective in young children, about 62% against severe infections. This is a good level of protection and it matters. Get a flu shot🧪 www.cidrap.umn.edu/influenza-va...

GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer's disease-like filaments www.pnas.org/doi/10.1073/...

Saying "AI is just a tool" does not mean you get to absolve yourself of thinking critically about the labor implications, or how LLMs trained on stolen work, or the water and power needs of the sector.

"But why won't you, academic, help improve the World Eating Plagiarism Death Sphere, that we built to destroy your field and our world and fund it through the theft of your work? Why are you so negative about it?"

I have a story out today about a remarkable woman named Linde Jacobs. Three years ago, at 33 years old, Linde found out that she carried a genetic mutation for a devastating brain disease, frontotemporal dementia, which begins in middle age. (Thread)