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Will CRISPR matter? @scienceboss.bsky.social captures the confusing energy of the gene-editing field today: Scientific advances & disillusioned investors Major hurdles remain to making CRISPR a sustainable modality in the drug industry. A must-read: endpts.com/biotech-is-s...

submitted 3 days ago • 0 comments

"Lithuania is a well-kept secret on the biotech scene,” Atrandi CEO Juozas Nainys told me. “There’s this vibe of what I imagine Silicon Valley was maybe 50, 60 years ago, or maybe in the early 2000s." My scoop on a Lithuanian biotech to watch: endpts.com/exclusive-li...

submitted 5 days ago • 0 comments

Europe can’t rely on the strength of the transatlantic relationship to help contain Russia’s threat – it must lead from the front and be the true force of support that Ukraine needs. Not just for Ukraine’s sake, but for a free and sovereign Europe.

submitted 8 days ago • 2400 comments

Method enables ultrafast protein labeling of tens of millions of densely packed cells www.lifescience.net/news/6181/me...

submitted 8 days ago • 0 comments

Boston/HK-based AI biotech Insilico Medicine released industry benchmarks—demonstrating an average 13-month timeline to preclinical drug candidate nomination, a reduction from the traditional 2.5- to 4-year process.

submitted 9 days ago • 0 comments

JUST IN: A startup Latent Labs, led by former DeepMind's lead scientist Dr. Simon Kohl, raised $50M to build AI foundation models for protein design 💰 🚀 Image credit: Latent Labs

submitted 10 days ago • 0 comments

Sometimes you just need to unplug and look above

submitted 11 days ago • 0 comments

Weekly Tech+Bio Highlights #28 This company sets new AI-driven drug discovery benchmarks, reducing preclinical timelines to as little as 9- 13 months to developmental candidate (DC) nomination—compared to the industry standard of 2.5–4 years www.techlifesci.com/p/weekly-tec...

submitted 11 days ago • 0 comments

How do you deal with information overload? I think our brain has not evolved to be constantly aware of how the entire word is doing? Constant global awareness is a pretty new state of being...

submitted 11 days ago • 0 comments

If you missed it, LinkedIn cofounder Reid Hoffman launched biotech startup Manas AI with $24.6M for AI drug discovery Notably, the other cofounder and CEO is Dr. Siddhartha Mukherjee, oncologist and author of The Emperor of All Maladies. I highly recommend the book!

submitted 15 days ago • 0 comments

If you are into aging research, here what the field looks like according to Vadym Gladyshev, one of the leading scientists there: "The main advances in aging research over the past decade were aging clocks and reprogramming" . It is what it is.

submitted 17 days ago • 0 comments

I think its pretty much a trend now when top tech executives launch AI drug discovery startups. Everyone wants to solve biology by computation... It seems possible for newcomers

submitted 19 days ago • 0 comments

I don't mean anything else but humour (credit: OstanniyCapitalist)

submitted 27 days ago • 0 comments

A sudden blow to the US-led AI dominance causes $1 trillion stock sell-off 😱 📉 If you somehow missed it, a Chinese AI startup, DeepSeek, has sent shockwaves through the tech industry with its new open-source AI model, R1.

submitted 27 days ago • 0 comments

That's called good old market "disruption," folks. The AI world's changed as most of the logic of the US AI strategy as well as logic of bigtech bros like OpenAI/Anthropic, and the logic of NVIDIA with its GPUs suddenly broke... What next? www.ft.com/content/e670...

submitted 27 days ago • 0 comments

That's my definition of AI drug discovery platform. Thoughts?

submitted 28 days ago • 0 comments

IMO, 2025 will be a year of big data deals in pharma. For a starter, Truveta raised $320M to sequence 10M exomes and build largest genetic database 📀 🧬 Data is king... validation is king... AI algorithms are already pretty good in AIxBio race.

submitted 28 days ago • 0 comments

Crazy, but rumors have it there might be a second $1B round for "AIxBio" startup in less than a year... According to report by Kyle LaHucik, Sam Altman's Retro Biosciences eyes $1B to extend lifespan via aiming its foundation model at cellular reprogramming. The other one was Xaira Tx...

submitted 29 days ago • 0 comments

"OpenAI's latest model consumes more electricity than Pittsburgh". "Microsoft's new AI datacenter will require 1 gigawatt of power—equivalent to powering 750,000 homes". (kudos to Ashu Garg for the insight: www.linkedin.com/feed/update/...) Yes, AI is hungry for energy.

submitted 30 days ago • 0 comments

“Great companies go through versions,” Sabry said. “They go through building their fundamental business in one direction. And then over time, these things change. That happened at Genentech. It’s happened to Roche, and it will happen to BioMarin as well.” endpts.com/biomarins-ja...

submitted 31 days ago • 0 comments

The impact of library size and scale of testing on virtual screening | Nature www.nature.com/articles/s41...

submitted 31 days ago • 0 comments

Yes, we have a Substack newsletter, if anything...

submitted 31 days ago • 0 comments

We clearly have a "innovation fetish", in science and tech. Some companies achieve breakthroughs and media is like "yeah, the good is around the corner" But it is implementation that takes years and decades, to translate lab breakthrogh into stuff that is available in daily life.

submitted 31 days ago • 0 comments

Cool news from gen AI camp in drug discovery: Boston based Insilico Medicine doses first patient with AI-designed pan-TEAD inhibitor. And by the way, they also just published first practical workflow of quantum computing in drug design! (comment for more details pls)

submitted 31 days ago • 0 comments

Wow, OpenAI enters cellular reprogramming space... It develops GPT-4b micro, an AI model designed to enhance protein engineering for stem cell reprogramming, increasing the efficiency of Yamanaka factors (arguably...) www.techlifesci.com/p/weekly-tec...

submitted 32 days ago • 0 comments

Probably, one of the largest collaborative efforts in biotech, since the Human Genome Project: the Human Cell Atlas has arrived! 🧬 This isn’t just another dataset—this is the blueprint of human biology, built cell by cell, tissue by tissue, organ by organ.

submitted 33 days ago • 0 comments

If you suddenly decided to start on a new media platform in 2025... just know this

submitted 35 days ago • 0 comments

Chip makers fight for new markets, and healthcare is lucrative as never before

submitted 35 days ago • 0 comments

The way Google enforces Geminy in its Gmail and Drive is irritating.

submitted 35 days ago • 0 comments

What is better, to have medical advice with potential errors every so often, but mostly correct, or have no advice at all?

submitted 41 days ago • 0 comments

No, its not California

submitted 41 days ago • 0 comments

IMO: Anyone who has not deepdived with ChatGPT o1 model, has no idea what AI is capable of and should not provide opinion about reasoning capabilities of modern day AI.

submitted 45 days ago • 0 comments

All 'true' AI drug discovery companies are actually software companies. We fantisize about AI as some kind of brain living in a jar... but the reality is, it is a software product, and should be treated as one. Anyone who claims they are AI-driven should be able to show GUI or feature spec. No?

submitted 45 days ago • 0 comments

So, we have four late stage clinical trial failures for “AI drug discovery” companies in just one month…

submitted 45 days ago • 0 comments

AI in biotech (vs. good old small molecules) is getting crowded...

submitted 47 days ago • 0 comments

Sad news from yet another 'AI-driven' drug discovery company... third since the year start 🧐 firstwordpharma.com/story/5925444

submitted 47 days ago • 0 comments

If AI system can screen and suggest the most optimal and safe drug-like molecule, it could also suggest the most toxic one. I have a curious study about it, let me know if this topic of interest...

submitted 47 days ago • 0 comments

Some trend in biotech/pharma 📝

submitted 49 days ago • 0 comments

My entire view of AI in bio is this: we already have sufficiently capable algo-s to improve drug discovery. But we do not have enough domain specific data to reach that. So, the race now is not for novel super AI, but for data acquisition capabilities. It is costly. Hence, huge $ valuations.

submitted 50 days ago • 0 comments

Small biotechs accounted for ~75% of new drug approvals, emphasizing external innovation's role, according to Atlas Venture report. And you thought it all were "Pfizers" and "GSKs" of this world"?

submitted 55 days ago • 1 comment