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alex-plum.bsky.social
Physics (Biophysics) PhD Candidate with Mattia Serra @UCSD Morphogenesis | Dynamical Systems | Origins
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Our paper on the E. coli Min system in vivo with @physicsoflifelmu.bsky.social & Judy Kim (UCSD) has been published in Nature Physics today. Tight integration of experiment and theory, and physiology and biophysics. Incredible perseverance of our young students. rdcu.be/ekIpO

Can using synthetic approaches to build biology help teach us the design principles of how embryos build themselves? 👷‍♀️🔧 If this is a question that interests you, come and share your thoughts at this Royal Society Workshop on Generative Biology www.royalsoc.ac.uk/science-even...

In developing embryos, cells move a lot! Plenty of that movement is random. Is random cell mixing a feature or bug for tissue patterning? Turns out, it’s both! Excited to share the 1st preprint from my postdoc w/ Sean Megason @seanemcgeary.bsky.social and Allon Klein. 1/20 doi.org/10.1101/2025...

Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...

ICYMI: Commentary on "mechanism" in dev bio Ozpolat et al argue for diverse approaches to mechanism - from molecular to systems level journals.biologists.com/dev/article/...

📣Check out our work led by @alex-plum.bsky.social ! We developed a mathematical framework for morphogen patterning in dynamic tissues, revealing key insights into how morphogenesis mediates cell-cell communication, morphogen compartmentalization and fate coordination. biorxiv.org/content/10.1...

📣 Excited to receive the 💥 NSF CAREER 💥 Award. Our group is looking for PhD students and postdocs interested in the Nonlinear Dynamics and the Physics of Living Systems, with support from NSF, HFSP, and other sources. We’d appreciate your help in spreading the word! @ucsdphysci.bsky.social

Mindscape 302 | Chris Kempes on the Biophysics of Evolution. Even squishy organisms are subject to the fundamental laws of nature. #MindscapePodcast www.preposterousuniverse.com/podcast/2025...

Chuai, M., Serrano Nájera, G., Serra, M., Mahadevan, L., & Weijer, C. J. (2023). Reconstruction of distinct vertebrate gastrulation modes via modulation of key cell behaviors in the chick embryo. Science Advances, 9(1), eabn5429. https://doi.org/10.1126/sciadv.abn5429 #EpithelialMechanics

Nájera, G. S., & Weijer, C. J. (2023). The evolution of gastrulation morphologies. Development, 150(7), dev200885. https://doi.org/10.1242/dev.200885 #EpithelialMechanicsReview

🦦 Feed your intellectual curiosity & challenge your limits at SFI’s Undergraduate Complexity Research program. Pursue new research directions and walk away with an unforgettable, transformative experience. Apply by January 14: apply-sfi.smapply.org/prog/ucr2025/

A stimulating workshop on the subject of Waddington Landscapes in Lyon last week, prompted me to compose some thoughts on dynamical landscapes, gene regulatory networks, and single cell transcriptomics briscoelab.org/morphogenalia/

Nothing like niche books at the La Jolla farmers market for $1