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alexisrohou.bsky.social
CryoEM and structural biology methods, drug discovery. Also: Celtics, Camus, rocksteady, drum and bass. He, him, his.
594 posts 1,502 followers 229 following
Prolific Poster

“Terrible things are happening outside. Poor helpless people are being dragged out of their homes. Families are torn apart. Men, women, and children are separated. Children come home from school to find that their parents have disappeared.” Diary of Anne Frank January 13, 1943

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.” A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world. www.cnn.com/2025/04/09/h...

Swinging lever mechanism of myosin shown by time-resolved cryoEM www.nature.com/articles/s41... so glad to finally be able to share this with the community! @astburycentre.bsky.social @astbury-bsl.bsky.social @stemuench.bsky.social @snmcmillan.bsky.social @davidklebl.bsky.social

Remember “climategate” with the email leaks? Here’s the best explanation of it, in some detail, I’ve ever come across. Great intro to climate science, and to science in general. podcasts.apple.com/us/podcast/c...

Donald Trump has committed the most profound, harmful and unnecessary economic error in the modern era. Almost everything he said—on history, economics and the technicalities of trade—was utterly deluded econ.st/3YbbFjq

www.biorxiv.org/content/10.1... NEW PREPRINT ALERT! Thanks to all involved!

Trump's 3/27 executive order targets the Smithsonian for advancing "the view that race is not a biological reality but a social construct." Trump argues that the exhibit's statement, below, is unscientific. He's wrong. As a biology professor and population geneticist, I agree with every word of it.

I’m a neutral and my heart barely made it through those 40 seconds.

AlphaFold, the revolutionary, Nobel prize-winning tool for predicting protein structures, has a problem: it’s running low on data https://go.nature.com/3FJRyTd

Gem from @pwk2024.bsky.social: who said there are no heroes in science?

In 25 years of covering national security, I’ve never seen a story like this: Senior Trump officials discussed planning for the U.S. attack on Yemen in a Signal group--and inadvertently added the editor-in-chief of The Atlantic. www.theatlantic.com/politics/arc...

So apparently violently storming the Capitol in an effort to overthrow an election = misguided high spirits, while firebombing a few Teslas = domestic terrorism.

The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉 You can find the full story here www.science.org/doi/10.1126/... @verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨

Aside from the obvious direct harm, what's so irritating is that a handful of spoiled ignorant assholes are breaking things that we all built together. They weren't content to own almost everything, they had to wreck what little they didn't own. It's vandalism on a mass scale and has to be punished

The specific quote from General John DeWitt, justifying Japanese internment: “The very fact that no sabotage has taken place to date is a disturbing and confirming indication that such action will be taken.”

Our Secretary of Defense almost certainly has more threatening/extremist tattoos and has more credibly been accused of sexual assault than almost all of the people being sent to El Salvador. No exaggeration.

Read this. The scale of death, inhumanity and evil being unleashed by Musk & Trump is hard to fathom. A Republican Party that claims to care about children, the golden rule or indeed ANY ethical code wouldn’t allow this. And yet they do. www.nytimes.com/interactive/...

Funny how it works. We have all these “lab leak” articles always starting with how they were “silenced”, “censored”, etc, etc. Yet, for years, all we hear about is the lab leak. Same nonsense over and over. Those *truly* being silenced are the scientists doing the work. Including in the NYTimes.

Take a moment today to read about a few of the young children whom Trump and Musk killed by shutting down USAID. The blame for these deaths falls on them. There will be hundreds of thousands more dead kids before their lethal crusade against foreign aid ends. www.nytimes.com/interactive/...

Sad news about Karen Davies' passing. Karen was an inspiration in bioenergetics and cryoET. Her pioneering postdoctoral work on ATP synthase and respiratory supercomplexes marked turning points in the field. I created Scholar profile to acknowledge her contribution scholar.google.com/citations?hl...

Anyone on the look out for life sciences roles should keep an eye out in the expanding Boston Biotech hub. In one new example, Roche will establish an Innovation Center on Harvard’s Research Campus in Allston, MA. The center will be 30,000 Sq. Ft. and employ up to 500 staff. 🧪🔬🧬 #Biotechnology

Remember those stories that tried to downplay RFK Jr’s deadly campaign against vaccines by saying that the Trump administration would make everybody healthy through access to fresh unprocessed food? How does canceling a billion dollars worth of local food for school and food banks fit with that?

“Washington has become the court of Nero,” Senator Claude Malhuret declared before the French Parliament this week. His speech, whose dark urgency and stark rhetorical force made it a social-media sensation, has been translated and adapted by The Atlantic:

Roche's open-source gift to the world of GPCRs and structural biology: scFv16. I wasn't aware of this history until Mazdak wrote it up...

French Senator Claude Malhuret: "Washington has become Nero’s court, with an incendiary emperor, submissive courtiers and a jester high on ketamine... We were at war with a dictator, we are now at war with a dictator backed by a traitor."

🧪what with the demolition of #NIH funded #research, where, dare I ask, are our friends from #bigpharma? y'all good? mooched enough off of public-access NIH-funded research? Stocked up with PhD level scientists who were trained on NIH training grants to tide you over until Academia comes back?

People will die. It’s notable that one big block of voters who made this possible is the “Christian” right. To potentially “save” some US fetuses from abortion, lots of foreigners will die of preventable causes.

Make a huge mistake. Then make a false claim about how you fixed it. They did it for PEPFAR. Now Ebola. I follow this particular topic VERY closely, so here's what really happened and why this isn't true AT ALL...🧵

US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks. https://go.nature.com/4kd1vIu

I have been trying to find the time to move away from the polical hellscape we find ourselves in to finish and share a bluetorial about science. This helps me remember what this is all about. Ironically, it is about the treatment of pain.

Dear California Representatives: Your leadership is more important than ever! We believe in your ability to make a difference—how can we support you in bringing more attention to this critical issue? @repscottpeters.bsky.social @levin.house.gov @schiff.senate.gov @padilla.senate.gov. Pls Repost!

BIG news: Jason Chin is leaving the Division of Protein & Nucleic Acid Chemistry of @mrclmb.bsky.social to spend yet another billionaire's ££ in Oxford. This will create a gap that will need filling! So, if you're thinking of making a move, now is the time to reach out! www.eit.org/news/profess...

💥The Netherlands' largest pension fund, has sold its shares in Tesla, Meta, and Alphabet (Google). The fund with US $569 billion equivolent in assets is "directing more money to companies and projects that help to improve society and the environment." #Divest www.reuters.com/markets/euro...

Open source software for the win. Generating plausible structural ensembles in a highly efficient manner could be very useful!

“the United States is not a startup. The federal government exists to do all of the things that are definitionally not profitable, that serve the public good rather than protect investor profits. (The vast majority of startups also fail, something the United States cannot afford to do.)”

A good analysis of the current economic success by integrating new neighbours (which is accompanied at the same time by great improvement in many social issues, although some more are needed) 👇 www.theguardian.com/world/2025/f...

Just wonderful writing on the 60 Minutes piece on President aMusk dismantling of USAID "The world's richest man cut off aid for the world's poorest people." Well done.

He has hollowed out the meaning of ‘saving your country’ and replaced it with something like ‘demolish those who disagree with me’. If he or anyone even tried to make the case that they really are trying to save the country (and from what), the whole thing would fall apart.

“When you dismiss children dying as a direct result of your actions as a “media narrative,” that is a good sign that you are an undiagnosed sociopath.”

The measles outbreak in Texas is reminding me of the public letter Roald Dahl wrote about losing his daughter to measles in 1962, just before the vaccine was publicly available.