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alissacg.bsky.social
Studying the spatial organization of brain tumors @ the Tirosh Lab @ the Weizmann Institute. Mother of 4. Lover of candy, art, & books.
14 posts 190 followers 126 following
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Tumor cells help each other out when amino acids are scarce www.nature.com/articles/s41...

Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature. We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social www.nature.com/articles/s41...

Delighted to share the published version of this work from brilliant #CancerNeuroscience post-doc Tara Barron detailing GABAergic neuron-to-glioma synapses in #DIPG/#DMG. 🧵 Open access link: www.nature.com/articles/s41...

Amazing to see this out. A mechanistic study with deep implications for future clinical work. Cannot be prouder.A huge thanks to all our collaborators an to Slim for driving this project www.nature.com/articles/s41... @sleemmz.bsky.social @ggargiul.bsky.social

Here's our latest - jointly with @rhaq1.bsky.social lab & co-lead by Drs. Schiantarelli, Benamar, Park et al - studying why some tumors stop responding to immunotherapy. This continues to be a tough puzzle to solve, but important for science & patients alike...

Lovely article on this fascinating field, which features some of my favorite people including @weissmanlab.bsky.social, @johnprensner.bsky.social, and others!

Spatial-Mux-seq is a multimodal spatial platform for simultaneously profiling the transcriptome, chromatin accessibility, histone modifications, and select proteins. www.nature.com/articles/s41...

Our paper “A genome-wide atlas of human cell morphology” is finally out today in @naturemethods.bsky.social ! www.nature.com/articles/s41... (I tweeted about our preprint in 2023 over at the bad place, but deactivated my account, so here we go again!)

Thrilled to share our recent work published in @naturegenet.bsky.social, where we uncover how ZIC1 is regulated by distinct genetic and epigenetic mechanisms in SHH vs. Group 4 medulloblastoma—revealing it as a context-dependent driver. tinyurl.com/2c3jnhn2

Here's our latest, led by Drs. Riaz Gillani & Ryan Collins - we studied a type of inherited genetic event (structural variants) + risk of developing certain cancers in kids: @danafarber.bsky.social @bostonchildrens.bsky.social @broadinstitute.org @science.org www.science.org/doi/10.1126/...

Delighted to share our perspective in @AnnualReviews on clarifying state/fate definitions & possibilities in cancer therapy resistance. Thanks @obenaufa.bsky.social for invite; we write a somewhat abstract/theoretical perspective. Would love to hear thoughts! www.annualreviews.org/content/jour...

Having a difficult day, but I'm glad to have microscopy to inspire me and hopefully inspire others as well. 💔 The brain keeps being amazing. These are neurons in the neocortex #FluorescenceFriday 🔬

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 10/20

How can we build an Al virtual cell that simulates all functions and interactions of a cell? How will it transform research and drive breakthroughs in programmable biology, drug discovery and personalized medicine? Take a look at our paper in @cellpress.bsky.social! www.cell.com/cell/fulltex...

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 9/20

This is spot on

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 8/20

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 7/20

Excited & flattered to see our work on the spatial organization of cancer cell states in brain tumors highlighted here!

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 6/20

"The lives of cells, recorded"--our new review on genomic recording systems and how they can reveal the dynamics of multicellular development. A pleasure to work on this with amazing colleagues from the Allen Discovery Center for Cell Lineage Tracing. www.nature.com/articles/s41...

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 6/20

Which one are you? Among scientists are collectors, classifiers, and compulsive tidiers-up; many are detectives by temperament and many are explorers; some are artists and others artisans. There are poet-scientists and philosopher-scientists and even a few mystics. –Peter Medawar

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 5/20

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 4/20

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 3/20

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 2/20

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #BookSky💙📚 #Books #BookChallenge Day 1/20